DNMBP-TPTE2 Fusion FISH Probe
The DNMBP-TPTE2 Fusion FISH Probe is used to confirm a fusion of the DNMBP and TPTE2 genes. The fusion of the DNMBP and TPTE2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNMBP-TPTE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-RERE | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-REOR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-REGO | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-REGR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-REAQ | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-ORRE | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-OROR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-ORGO | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GORE | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GOOR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GOGO | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GOGR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GRRE | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GROR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GRGO | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GRGR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-AQRE | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-AQOR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-AQGO | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-AQGR | 20 (40 μL) | 200 μL |
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| DNMBP-TPTE2-20-AQAQ | 20 (40 μL) | 200 μL |
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DNMBP Gene Summary
This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Dynamin Binding Protein
Chromosome: CHR10: 101635333 -101769676
Locus: 10q24.2
TPTE2 Gene Summary
TPIP is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids.[supplied by OMIM, Jul 2002]
Gene Name: Transmembrane Phosphoinositide 3-phosphatase And Tensin Homolog 2
Chromosome: CHR13: 19997018 -20110903
Locus: 13q12.11
Gene Diseases
The DNMBP TPTE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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