DNM3-CD247 Fusion FISH Probe
The DNM3-CD247 Fusion FISH Probe is used to confirm a fusion of the DNM3 and CD247 genes. The fusion of the DNM3 and CD247 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNM3-CD247-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-RERE | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-REOR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-REGO | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-REGR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-REAQ | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-ORRE | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-OROR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-ORGO | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GORE | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GOOR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GOGO | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GOGR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GRRE | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GROR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GRGO | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GRGR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-AQRE | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-AQOR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-AQGO | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-AQGR | 20 (40 μL) | 200 μL |
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| DNM3-CD247-20-AQAQ | 20 (40 μL) | 200 μL |
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CD247 Gene Summary
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: CD247 Molecule
Chromosome: CHR1: 167399876 -167487847
Locus: 1q24.2
DNM3 Gene Summary
This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: Dynamin 3
Chromosome: CHR1: 171810620 -172381857
Locus: 1q24.3
Gene Diseases
The DNM3 CD247 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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