DNM2-PTH2R Fusion FISH Probe
The DNM2-PTH2R Fusion FISH Probe is used to confirm a fusion of the DNM2 and PTH2R genes. The fusion of the DNM2 and PTH2R genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNM2-PTH2R-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-RERE | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-REOR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-REGO | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-REGR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-REAQ | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-ORRE | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-OROR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-ORGO | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GORE | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GOOR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GOGO | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GOGR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GRRE | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GROR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GRGO | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GRGR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-AQRE | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-AQOR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-AQGO | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-AQGR | 20 (40 μL) | 200 μL |
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| DNM2-PTH2R-20-AQAQ | 20 (40 μL) | 200 μL |
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DNM2 Gene Summary
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
Gene Name: Dynamin 2
Chromosome: CHR19: 10828728 -10942586
Locus: 19p13.2
PTH2R Gene Summary
The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Name: Parathyroid Hormone 2 Receptor
Chromosome: CHR2: 209271555 -209359231
Locus: 2q34
Gene Diseases
The DNM2 PTH2R Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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