DNM2-ARHGAP25 Fusion FISH Probe
The DNM2-ARHGAP25 Fusion FISH Probe is used to confirm a fusion of the DNM2 and ARHGAP25 genes. The fusion of the DNM2 and ARHGAP25 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DNM2-ARHGAP25-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DNM2-ARHGAP25-20-AQAQ | 20 (40 μL) | 200 μL |
|
DNM2 Gene Summary
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
Gene Name: Dynamin 2
Chromosome: CHR19: 10828728 -10942586
Locus: 19p13.2
ARHGAP25 Gene Summary
ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 25
Chromosome: CHR2: 68961912 -69053957
Locus: 2p13.3
Gene Diseases
The DNM2 ARHGAP25 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|