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DNM1L-CAP2 Fusion FISH Probe

The DNM1L-CAP2 Fusion FISH Probe is used to confirm a fusion of the DNM1L and CAP2 genes. The fusion of the DNM1L and CAP2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DNM1L-CAP2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DNM1L-CAP2-20-RERE 20 (40 μL) 200 μL
DNM1L-CAP2-20-REOR 20 (40 μL) 200 μL
DNM1L-CAP2-20-REGO 20 (40 μL) 200 μL
DNM1L-CAP2-20-REGR 20 (40 μL) 200 μL
DNM1L-CAP2-20-REAQ 20 (40 μL) 200 μL
DNM1L-CAP2-20-ORRE 20 (40 μL) 200 μL
DNM1L-CAP2-20-OROR 20 (40 μL) 200 μL
DNM1L-CAP2-20-ORGO 20 (40 μL) 200 μL
DNM1L-CAP2-20-ORAQ 20 (40 μL) 200 μL
DNM1L-CAP2-20-GORE 20 (40 μL) 200 μL
DNM1L-CAP2-20-GOOR 20 (40 μL) 200 μL
DNM1L-CAP2-20-GOGO 20 (40 μL) 200 μL
DNM1L-CAP2-20-GOGR 20 (40 μL) 200 μL
DNM1L-CAP2-20-GOAQ 20 (40 μL) 200 μL
DNM1L-CAP2-20-GRRE 20 (40 μL) 200 μL
DNM1L-CAP2-20-GROR 20 (40 μL) 200 μL
DNM1L-CAP2-20-GRGO 20 (40 μL) 200 μL
DNM1L-CAP2-20-GRGR 20 (40 μL) 200 μL
DNM1L-CAP2-20-GRAQ 20 (40 μL) 200 μL
DNM1L-CAP2-20-AQRE 20 (40 μL) 200 μL
DNM1L-CAP2-20-AQOR 20 (40 μL) 200 μL
DNM1L-CAP2-20-AQGO 20 (40 μL) 200 μL
DNM1L-CAP2-20-AQGR 20 (40 μL) 200 μL
DNM1L-CAP2-20-AQAQ 20 (40 μL) 200 μL

DNM1L Gene Summary

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Gene Name: Dynamin 1 Like

Chromosome: CHR12: 32832136 -32898584

Locus: 12p11.21

CAP2 Gene Summary

This gene was identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl cyclase-associated protein and actin. [provided by RefSeq, Jul 2008]

Gene Name: Cyclase Associated Actin Cytoskeleton Regulatory Protein 2

Chromosome: CHR6: 17393735 -17558023

Locus: 6p22.3

Gene Diseases

The DNM1L CAP2 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.