DNAJC7-TBCD Fusion FISH Probe
The DNAJC7-TBCD Fusion FISH Probe is used to confirm a fusion of the DNAJC7 and TBCD genes. The fusion of the DNAJC7 and TBCD genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNAJC7-TBCD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-RERE | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-REOR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-REGO | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-REGR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-REAQ | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-ORRE | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-OROR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-ORGO | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GORE | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GOOR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GOGO | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GOGR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GRRE | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GROR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GRGO | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GRGR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-AQRE | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-AQOR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-AQGO | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-AQGR | 20 (40 μL) | 200 μL |
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| DNAJC7-TBCD-20-AQAQ | 20 (40 μL) | 200 μL |
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TBCD Gene Summary
Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008]
Gene Name: Tubulin Folding Cofactor D
Chromosome: CHR17: 80709939 -80901062
Locus: 17q25.3
DNAJC7 Gene Summary
This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C7
Chromosome: CHR17: 40128438 -40169715
Locus: 17q21.2
Gene Diseases
The DNAJC7 TBCD Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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