DNAJC6-PDE1C Fusion FISH Probe
The DNAJC6-PDE1C Fusion FISH Probe is used to confirm a fusion of the DNAJC6 and PDE1C genes. The fusion of the DNAJC6 and PDE1C genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNAJC6-PDE1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-RERE | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-REOR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-REGO | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-REGR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-REAQ | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-ORRE | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-OROR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-ORGO | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GORE | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GOOR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GOGO | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GOGR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GRRE | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GROR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GRGO | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GRGR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-AQRE | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-AQOR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-AQGO | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-AQGR | 20 (40 μL) | 200 μL |
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| DNAJC6-PDE1C-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE1C Gene Summary
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]
Gene Name: Phosphodiesterase 1C
Chromosome: CHR7: 31792631 -32338383
Locus: 7p14.3
DNAJC6 Gene Summary
DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C6
Chromosome: CHR1: 65730429 -65881552
Locus: 1p31.3
Gene Diseases
The DNAJC6 PDE1C Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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