DNAJC21-SGCZ Fusion FISH Probe
The DNAJC21-SGCZ Fusion FISH Probe is used to confirm a fusion of the DNAJC21 and SGCZ genes. The fusion of the DNAJC21 and SGCZ genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNAJC21-SGCZ-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-RERE | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-REOR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-REGO | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-REGR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-REAQ | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-ORRE | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-OROR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-ORGO | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GORE | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GOOR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GOGO | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GOGR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GRRE | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GROR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GRGO | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GRGR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-AQRE | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-AQOR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-AQGO | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-AQGR | 20 (40 μL) | 200 μL |
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| DNAJC21-SGCZ-20-AQAQ | 20 (40 μL) | 200 μL |
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DNAJC21 Gene Summary
This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the precursor 45S ribosomal RNA and may be involved in early nuclear ribosomal RNA biogenesis and maturation of the 60S ribosomal subunit. Mutations in this gene result in Bone marrow failure syndrome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2017]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C21
Chromosome: CHR5: 34929697 -34959069
Locus: 5p13.2
SGCZ Gene Summary
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix. [provided by RefSeq, Jul 2008]
Gene Name: Sarcoglycan Zeta
Chromosome: CHR8: 13947372 -15095792
Locus: 8p22
Gene Diseases
The DNAJC21 SGCZ Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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