DNAJC2-RELN Fusion FISH Probe
The DNAJC2-RELN Fusion FISH Probe is used to confirm a fusion of the DNAJC2 and RELN genes. The fusion of the DNAJC2 and RELN genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNAJC2-RELN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-RERE | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-REOR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-REGO | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-REGR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-REAQ | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-ORRE | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-OROR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-ORGO | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GORE | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GOOR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GOGO | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GOGR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GRRE | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GROR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GRGO | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GRGR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-AQRE | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-AQOR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-AQGO | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-AQGR | 20 (40 μL) | 200 μL |
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| DNAJC2-RELN-20-AQAQ | 20 (40 μL) | 200 μL |
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RELN Gene Summary
This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Reelin
Chromosome: CHR7: 103112230 -103629963
Locus: 7q22.1
DNAJC2 Gene Summary
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C2
Chromosome: CHR7: 102952920 -102985320
Locus: 7q22.1
Gene Diseases
The DNAJC2 RELN Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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