DNAJC2-CDK14 Fusion FISH Probe
The DNAJC2-CDK14 Fusion FISH Probe is used to confirm a fusion of the DNAJC2 and CDK14 genes. The fusion of the DNAJC2 and CDK14 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNAJC2-CDK14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-RERE | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-REOR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-REGO | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-REGR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-REAQ | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-ORRE | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-OROR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-ORGO | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GORE | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GOOR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GOGO | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GOGR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GRRE | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GROR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GRGO | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GRGR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-AQRE | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-AQOR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-AQGO | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-AQGR | 20 (40 μL) | 200 μL |
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| DNAJC2-CDK14-20-AQAQ | 20 (40 μL) | 200 μL |
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CDK14 Gene Summary
PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]
Gene Name: Cyclin Dependent Kinase 14
Chromosome: CHR7: 90338711 -90839904
Locus: 7q21.13
DNAJC2 Gene Summary
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C2
Chromosome: CHR7: 102952920 -102985320
Locus: 7q22.1
Gene Diseases
The DNAJC2 CDK14 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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