DNAJC1-DCLRE1C Fusion FISH Probe
The DNAJC1-DCLRE1C Fusion FISH Probe is used to confirm a fusion of the DNAJC1 and DCLRE1C genes. The fusion of the DNAJC1 and DCLRE1C genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DNAJC1-DCLRE1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-RERE | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-REOR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-REGO | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-REGR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-REAQ | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-ORRE | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-OROR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-ORGO | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GORE | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GOOR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GOGO | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GOGR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GRRE | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GROR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GRGO | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GRGR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-AQRE | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-AQOR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-AQGO | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-AQGR | 20 (40 μL) | 200 μL |
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| DNAJC1-DCLRE1C-20-AQAQ | 20 (40 μL) | 200 μL |
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DNAJC1 Gene Summary
The membrane protein encoded by this gene is a DNAJ-like heat shock protein that binds the molecular chaperone BiP. In addition, the encoded protein contains two SANT domains that have been shown to bind serpin alpha1-antichymotrypsin and inter-alpha trypsin inhibitor heavy chain 4. [provided by RefSeq, Jul 2016]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C1
Chromosome: CHR10: 22045476 -22292650
Locus: 10p12.31
DCLRE1C Gene Summary
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Name: DNA Cross-link Repair 1C
Chromosome: CHR10: 14948870 -14996094
Locus: 10p13
Gene Diseases
The DNAJC1 DCLRE1C Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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