DMBT1-ARMS2 Fusion FISH Probe
The DMBT1-ARMS2 Fusion FISH Probe is used to confirm a fusion of the DMBT1 and ARMS2 genes. The fusion of the DMBT1 and ARMS2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DMBT1-ARMS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-RERE | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-REOR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-REGO | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-REGR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-REAQ | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-ORRE | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-OROR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-ORGO | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GORE | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GOOR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GOGO | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GOGR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GRRE | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GROR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GRGO | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GRGR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-AQRE | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-AQOR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-AQGO | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-AQGR | 20 (40 μL) | 200 μL |
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| DMBT1-ARMS2-20-AQAQ | 20 (40 μL) | 200 μL |
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DMBT1 Gene Summary
Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016]
Gene Name: Deleted In Malignant Brain Tumors 1
Chromosome: CHR10: 124320180 -124403252
Locus: 10q26.13
ARMS2 Gene Summary
This gene encodes a small secreted protein specific to primates. This protein is a component of the choroidal extracellular matrix of the eye. Mutations in this gene are associated with age-related macular degeneration. [provided by RefSeq, Sep 2017]
Gene Name: Age-related Maculopathy Susceptibility 2
Chromosome: CHR10: 124214178 -124216868
Locus: 10q26.13
Gene Diseases
The DMBT1 ARMS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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