DLG4-KRT8 Fusion FISH Probe
The DLG4-KRT8 Fusion FISH Probe is used to confirm a fusion of the DLG4 and KRT8 genes. The fusion of the DLG4 and KRT8 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DLG4-KRT8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-RERE | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-REOR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-REGO | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-REGR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-REAQ | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-ORRE | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-OROR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-ORGO | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-ORAQ | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GORE | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GOOR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GOGO | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GOGR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GOAQ | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GRRE | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GROR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GRGO | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GRGR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-GRAQ | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-AQRE | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-AQOR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-AQGO | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-AQGR | 20 (40 μL) | 200 μL |
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| DLG4-KRT8-20-AQAQ | 20 (40 μL) | 200 μL |
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DLG4 Gene Summary
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Discs Large MAGUK Scaffold Protein 4
Chromosome: CHR17: 7093209 -7123369
Locus: 17p13.1
KRT8 Gene Summary
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Keratin 8
Chromosome: CHR12: 53290970 -53298868
Locus: 12q13.13
Gene Diseases
The DLG4 KRT8 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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