DLG1-PCSK5 Fusion FISH Probe
The DLG1-PCSK5 Fusion FISH Probe is used to confirm a fusion of the DLG1 and PCSK5 genes. The fusion of the DLG1 and PCSK5 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DLG1-PCSK5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-RERE | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-REOR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-REGO | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-REGR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-REAQ | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-ORRE | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-OROR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-ORGO | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-ORAQ | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GORE | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GOOR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GOGO | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GOGR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GOAQ | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GRRE | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GROR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GRGO | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GRGR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-GRAQ | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-AQRE | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-AQOR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-AQGO | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-AQGR | 20 (40 μL) | 200 μL |
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| DLG1-PCSK5-20-AQAQ | 20 (40 μL) | 200 μL |
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DLG1 Gene Summary
This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known. [provided by RefSeq, Feb 2011]
Gene Name: Discs Large MAGUK Scaffold Protein 1
Chromosome: CHR3: 196769430 -197025447
Locus: 3q29
PCSK5 Gene Summary
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER. It then sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. This encoded protein is widely expressed and one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It mediates posttranslational endoproteolytic processing for several integrin alpha subunits and is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Alternative splicing results in multiple transcript variants, some of which encode distinct isoforms, including a protease packaged into dense core granules (PC5A) and a type 1 membrane bound protease (PC5B). [provided by RefSeq, May 2014]
Gene Name: Proprotein Convertase Subtilisin/kexin Type 5
Chromosome: CHR9: 78505559 -78977255
Locus: 9q21.13
Gene Diseases
The DLG1 PCSK5 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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