DLG1-MYO9B Fusion FISH Probe
The DLG1-MYO9B Fusion FISH Probe is used to confirm a fusion of the DLG1 and MYO9B genes. The fusion of the DLG1 and MYO9B genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DLG1-MYO9B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-RERE | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-REOR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-REGO | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-REGR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-REAQ | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-ORRE | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-OROR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-ORGO | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-ORAQ | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GORE | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GOOR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GOGO | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GOGR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GOAQ | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GRRE | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GROR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GRGO | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GRGR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-GRAQ | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-AQRE | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-AQOR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-AQGO | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-AQGR | 20 (40 μL) | 200 μL |
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| DLG1-MYO9B-20-AQAQ | 20 (40 μL) | 200 μL |
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DLG1 Gene Summary
This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known. [provided by RefSeq, Feb 2011]
Gene Name: Discs Large MAGUK Scaffold Protein 1
Chromosome: CHR3: 196769430 -197025447
Locus: 3q29
MYO9B Gene Summary
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin IXB
Chromosome: CHR19: 17186590 -17324104
Locus: 19p13.11
Gene Diseases
The DLG1 MYO9B Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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