DLG1-BDH1 Fusion FISH Probe
The DLG1-BDH1 Fusion FISH Probe is used to confirm a fusion of the DLG1 and BDH1 genes. The fusion of the DLG1 and BDH1 genes has been associated with Lung Squamous Cell Carcinoma, Esophageal Carcinoma, Head And Neck Squamous Cell Carcinoma , and Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DLG1-BDH1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-RERE | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-REOR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-REGO | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-REGR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-REAQ | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-ORRE | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-OROR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-ORGO | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GORE | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GOOR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GOGO | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GOGR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GRRE | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GROR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GRGO | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GRGR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-AQRE | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-AQOR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-AQGO | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-AQGR | 20 (40 μL) | 200 μL |
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| DLG1-BDH1-20-AQAQ | 20 (40 μL) | 200 μL |
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BDH1 Gene Summary
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Name: 3-hydroxybutyrate Dehydrogenase 1
Chromosome: CHR3: 197236653 -197300194
Locus: 3q29
DLG1 Gene Summary
This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known. [provided by RefSeq, Feb 2011]
Gene Name: Discs Large MAGUK Scaffold Protein 1
Chromosome: CHR3: 196769430 -197025447
Locus: 3q29
Gene Diseases
The DLG1 BDH1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Esophageal Carcinoma |
| Head And Neck Squamous Cell Carcinoma |
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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