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DLG1-BDH1 Fusion FISH Probe

The DLG1-BDH1 Fusion FISH Probe is used to confirm a fusion of the DLG1 and BDH1 genes. The fusion of the DLG1 and BDH1 genes has been associated with Lung Squamous Cell Carcinoma, Esophageal Carcinoma, Head And Neck Squamous Cell Carcinoma , and Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DLG1-BDH1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DLG1-BDH1-20-RERE 20 (40 μL) 200 μL
DLG1-BDH1-20-REOR 20 (40 μL) 200 μL
DLG1-BDH1-20-REGO 20 (40 μL) 200 μL
DLG1-BDH1-20-REGR 20 (40 μL) 200 μL
DLG1-BDH1-20-REAQ 20 (40 μL) 200 μL
DLG1-BDH1-20-ORRE 20 (40 μL) 200 μL
DLG1-BDH1-20-OROR 20 (40 μL) 200 μL
DLG1-BDH1-20-ORGO 20 (40 μL) 200 μL
DLG1-BDH1-20-ORAQ 20 (40 μL) 200 μL
DLG1-BDH1-20-GORE 20 (40 μL) 200 μL
DLG1-BDH1-20-GOOR 20 (40 μL) 200 μL
DLG1-BDH1-20-GOGO 20 (40 μL) 200 μL
DLG1-BDH1-20-GOGR 20 (40 μL) 200 μL
DLG1-BDH1-20-GOAQ 20 (40 μL) 200 μL
DLG1-BDH1-20-GRRE 20 (40 μL) 200 μL
DLG1-BDH1-20-GROR 20 (40 μL) 200 μL
DLG1-BDH1-20-GRGO 20 (40 μL) 200 μL
DLG1-BDH1-20-GRGR 20 (40 μL) 200 μL
DLG1-BDH1-20-GRAQ 20 (40 μL) 200 μL
DLG1-BDH1-20-AQRE 20 (40 μL) 200 μL
DLG1-BDH1-20-AQOR 20 (40 μL) 200 μL
DLG1-BDH1-20-AQGO 20 (40 μL) 200 μL
DLG1-BDH1-20-AQGR 20 (40 μL) 200 μL
DLG1-BDH1-20-AQAQ 20 (40 μL) 200 μL

BDH1 Gene Summary

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Gene Name: 3-hydroxybutyrate Dehydrogenase 1

Chromosome: CHR3: 197236653 -197300194

Locus: 3q29

DLG1 Gene Summary

This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known. [provided by RefSeq, Feb 2011]

Gene Name: Discs Large MAGUK Scaffold Protein 1

Chromosome: CHR3: 196769430 -197025447

Locus: 3q29

Gene Diseases

The DLG1 BDH1 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma
Esophageal Carcinoma
Head And Neck Squamous Cell Carcinoma 
Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.