DLD-SCEL Fusion FISH Probe
The DLD-SCEL Fusion FISH Probe is used to confirm a fusion of the DLD and SCEL genes. The fusion of the DLD and SCEL genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DLD-SCEL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-RERE | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-REOR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-REGO | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-REGR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-REAQ | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-ORRE | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-OROR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-ORGO | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-ORAQ | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GORE | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GOOR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GOGO | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GOGR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GOAQ | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GRRE | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GROR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GRGO | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GRGR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-GRAQ | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-AQRE | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-AQOR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-AQGO | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-AQGR | 20 (40 μL) | 200 μL |
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| DLD-SCEL-20-AQAQ | 20 (40 μL) | 200 μL |
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DLD Gene Summary
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Name: Dihydrolipoamide Dehydrogenase
Chromosome: CHR7: 107531585 -107561643
Locus: 7q31.1
SCEL Gene Summary
The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Sciellin
Chromosome: CHR13: 78109808 -78219398
Locus: 13q22.3
Gene Diseases
The DLD SCEL Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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