DISC1-MDM1 Fusion FISH Probe
The DISC1-MDM1 Fusion FISH Probe is used to confirm a fusion of the DISC1 and MDM1 genes. The fusion of the DISC1 and MDM1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DISC1-MDM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-RERE | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-REOR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-REGO | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-REGR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-REAQ | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-ORRE | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-OROR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-ORGO | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GORE | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GOOR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GOGO | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GOGR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GRRE | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GROR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GRGO | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GRGR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-AQRE | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-AQOR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-AQGO | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-AQGR | 20 (40 μL) | 200 μL |
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| DISC1-MDM1-20-AQAQ | 20 (40 μL) | 200 μL |
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DISC1 Gene Summary
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Disrupted In Schizophrenia 1
Chromosome: CHR1: 231762560 -232177019
Locus: 1q42.2
MDM1 Gene Summary
This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells, and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. naturally occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Aug 2017]
Gene Name: Mdm1 Nuclear Protein
Chromosome: CHR12: 68688345 -68726161
Locus: 12q15
Gene Diseases
The DISC1 MDM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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