DIS3L2-SPHKAP Fusion FISH Probe
The DIS3L2-SPHKAP Fusion FISH Probe is used to confirm a fusion of the DIS3L2 and SPHKAP genes. The fusion of the DIS3L2 and SPHKAP genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DIS3L2-SPHKAP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-RERE | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-REOR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-REGO | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-REGR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-REAQ | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-ORRE | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-OROR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-ORGO | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-ORAQ | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GORE | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GOOR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GOGO | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GOGR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GOAQ | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GRRE | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GROR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GRGO | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GRGR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-GRAQ | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-AQRE | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-AQOR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-AQGO | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-AQGR | 20 (40 μL) | 200 μL |
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| DIS3L2-SPHKAP-20-AQAQ | 20 (40 μL) | 200 μL |
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SPHKAP Gene Summary
The SPHK1 Interactor, AKAP Domain Containing (SPHKAP) gene is located on chr2 :228844669-229046361 at 2q36.3.
Gene Name: SPHK1 Interactor, AKAP Domain Containing
Chromosome: CHR2: 228844669 -229046361
Locus: 2q36.3
DIS3L2 Gene Summary
The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Mar 2012]
Gene Name: DIS3 Like 3'-5' Exoribonuclease 2
Chromosome: CHR2: 232826292 -233201908
Locus: 2q37.1
Gene Diseases
The DIS3L2 SPHKAP Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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