DIP2B-TAF8 Fusion FISH Probe
The DIP2B-TAF8 Fusion FISH Probe is used to confirm a fusion of the DIP2B and TAF8 genes. The fusion of the DIP2B and TAF8 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DIP2B-TAF8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-RERE | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-REOR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-REGO | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-REGR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-REAQ | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-ORRE | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-OROR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-ORGO | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-ORAQ | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GORE | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GOOR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GOGO | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GOGR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GOAQ | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GRRE | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GROR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GRGO | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GRGR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-GRAQ | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-AQRE | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-AQOR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-AQGO | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-AQGR | 20 (40 μL) | 200 μL |
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| DIP2B-TAF8-20-AQAQ | 20 (40 μL) | 200 μL |
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DIP2B Gene Summary
This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]
Gene Name: Disco Interacting Protein 2 Homolog B
Chromosome: CHR12: 50898767 -51142450
Locus: 12q13.12
TAF8 Gene Summary
This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: TATA-box Binding Protein Associated Factor 8
Chromosome: CHR6: 42018250 -42048644
Locus: 6p21.1
Gene Diseases
The DIP2B TAF8 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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