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DIP2B-LARP4 Fusion FISH Probe

The DIP2B-LARP4 Fusion FISH Probe is used to confirm a fusion of the DIP2B and LARP4 genes. The fusion of the DIP2B and LARP4 genes has been associated with Ovarian Serous Cystadenocarcinoma, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DIP2B-LARP4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DIP2B-LARP4-20-RERE 20 (40 μL) 200 μL
DIP2B-LARP4-20-REOR 20 (40 μL) 200 μL
DIP2B-LARP4-20-REGO 20 (40 μL) 200 μL
DIP2B-LARP4-20-REGR 20 (40 μL) 200 μL
DIP2B-LARP4-20-REAQ 20 (40 μL) 200 μL
DIP2B-LARP4-20-ORRE 20 (40 μL) 200 μL
DIP2B-LARP4-20-OROR 20 (40 μL) 200 μL
DIP2B-LARP4-20-ORGO 20 (40 μL) 200 μL
DIP2B-LARP4-20-ORAQ 20 (40 μL) 200 μL
DIP2B-LARP4-20-GORE 20 (40 μL) 200 μL
DIP2B-LARP4-20-GOOR 20 (40 μL) 200 μL
DIP2B-LARP4-20-GOGO 20 (40 μL) 200 μL
DIP2B-LARP4-20-GOGR 20 (40 μL) 200 μL
DIP2B-LARP4-20-GOAQ 20 (40 μL) 200 μL
DIP2B-LARP4-20-GRRE 20 (40 μL) 200 μL
DIP2B-LARP4-20-GROR 20 (40 μL) 200 μL
DIP2B-LARP4-20-GRGO 20 (40 μL) 200 μL
DIP2B-LARP4-20-GRGR 20 (40 μL) 200 μL
DIP2B-LARP4-20-GRAQ 20 (40 μL) 200 μL
DIP2B-LARP4-20-AQRE 20 (40 μL) 200 μL
DIP2B-LARP4-20-AQOR 20 (40 μL) 200 μL
DIP2B-LARP4-20-AQGO 20 (40 μL) 200 μL
DIP2B-LARP4-20-AQGR 20 (40 μL) 200 μL
DIP2B-LARP4-20-AQAQ 20 (40 μL) 200 μL

DIP2B Gene Summary

This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]

Gene Name: Disco Interacting Protein 2 Homolog B

Chromosome: CHR12: 50898767 -51142450

Locus: 12q13.12

LARP4 Gene Summary

The La Ribonucleoprotein Domain Family Member 4 (LARP4) gene is located on chr12 :50794591-50873788 at 12q13.12.

Gene Name: La Ribonucleoprotein Domain Family Member 4

Chromosome: CHR12: 50794591 -50873788

Locus: 12q13.12

Gene Diseases

The DIP2B LARP4 Fusion has been associated with the following diseases:

Disease Name
Ovarian Serous Cystadenocarcinoma
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.