DICER1-SAMD4A Fusion FISH Probe
The DICER1-SAMD4A Fusion FISH Probe is used to confirm a fusion of the DICER1 and SAMD4A genes. The fusion of the DICER1 and SAMD4A genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DICER1-SAMD4A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-RERE | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-REOR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-REGO | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-REGR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-REAQ | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-ORRE | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-OROR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-ORGO | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-ORAQ | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GORE | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GOOR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GOGO | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GOGR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GOAQ | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GRRE | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GROR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GRGO | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GRGR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-GRAQ | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-AQRE | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-AQOR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-AQGO | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-AQGR | 20 (40 μL) | 200 μL |
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| DICER1-SAMD4A-20-AQAQ | 20 (40 μL) | 200 μL |
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SAMD4A Gene Summary
Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008]
Gene Name: Sterile Alpha Motif Domain Containing 4A
Chromosome: CHR14: 55034329 -55260033
Locus: 14q22.2
DICER1 Gene Summary
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
Gene Name: Dicer 1, Ribonuclease III
Chromosome: CHR14: 95552564 -95623759
Locus: 14q32.13
Gene Diseases
The DICER1 SAMD4A Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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