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DICER1-PAPOLA Fusion FISH Probe

The DICER1-PAPOLA Fusion FISH Probe is used to confirm a fusion of the DICER1 and PAPOLA genes. The fusion of the DICER1 and PAPOLA genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DICER1-PAPOLA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DICER1-PAPOLA-20-RERE 20 (40 μL) 200 μL
DICER1-PAPOLA-20-REOR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-REGO 20 (40 μL) 200 μL
DICER1-PAPOLA-20-REGR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-REAQ 20 (40 μL) 200 μL
DICER1-PAPOLA-20-ORRE 20 (40 μL) 200 μL
DICER1-PAPOLA-20-OROR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-ORGO 20 (40 μL) 200 μL
DICER1-PAPOLA-20-ORAQ 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GORE 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GOOR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GOGO 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GOGR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GOAQ 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GRRE 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GROR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GRGO 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GRGR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-GRAQ 20 (40 μL) 200 μL
DICER1-PAPOLA-20-AQRE 20 (40 μL) 200 μL
DICER1-PAPOLA-20-AQOR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-AQGO 20 (40 μL) 200 μL
DICER1-PAPOLA-20-AQGR 20 (40 μL) 200 μL
DICER1-PAPOLA-20-AQAQ 20 (40 μL) 200 μL

PAPOLA Gene Summary

The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition of adenosine residues for the creation of the 3'-poly(A) tail of mRNAs. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Gene Name: Poly(A) Polymerase Alpha

Chromosome: CHR14: 96968719 -97033448

Locus: 14q32.2

DICER1 Gene Summary

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

Gene Name: Dicer 1, Ribonuclease III

Chromosome: CHR14: 95552564 -95623759

Locus: 14q32.13

Gene Diseases

The DICER1 PAPOLA Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.