DICER1-PAPOLA Fusion FISH Probe
The DICER1-PAPOLA Fusion FISH Probe is used to confirm a fusion of the DICER1 and PAPOLA genes. The fusion of the DICER1 and PAPOLA genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
DICER1-PAPOLA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-RERE | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-REOR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-REGO | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-REGR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-REAQ | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-ORRE | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-OROR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-ORGO | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-ORAQ | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GORE | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GOOR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GOGO | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GOGR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GOAQ | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GRRE | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GROR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GRGO | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GRGR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-GRAQ | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-AQRE | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-AQOR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-AQGO | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-AQGR | 20 (40 μL) | 200 μL | ||
DICER1-PAPOLA-20-AQAQ | 20 (40 μL) | 200 μL |
PAPOLA Gene Summary
The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition of adenosine residues for the creation of the 3'-poly(A) tail of mRNAs. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Poly(A) Polymerase Alpha
Chromosome: CHR14: 96968719 -97033448
Locus: 14q32.2
DICER1 Gene Summary
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
Gene Name: Dicer 1, Ribonuclease III
Chromosome: CHR14: 95552564 -95623759
Locus: 14q32.13
Gene Diseases
The DICER1 PAPOLA Fusion has been associated with the following diseases:
Disease Name |
---|
Lung Squamous Cell Carcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|