DIAPH2-MAGEA11 Fusion FISH Probe
The DIAPH2-MAGEA11 Fusion FISH Probe is used to confirm a fusion of the DIAPH2 and MAGEA11 genes. The fusion of the DIAPH2 and MAGEA11 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DIAPH2-MAGEA11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-RERE | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-REOR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-REGO | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-REGR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-REAQ | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-ORRE | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-OROR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-ORGO | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-ORAQ | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GORE | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GOOR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GOGO | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GOGR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GOAQ | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GRRE | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GROR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GRGO | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GRGR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-GRAQ | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-AQRE | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-AQOR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-AQGO | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-AQGR | 20 (40 μL) | 200 μL |
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| DIAPH2-MAGEA11-20-AQAQ | 20 (40 μL) | 200 μL |
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DIAPH2 Gene Summary
The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Diaphanous Related Formin 2
Chromosome: CHRX: 95939661 -96855597
Locus: Xq21.33
MAGEA11 Gene Summary
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: MAGE Family Member A11
Chromosome: CHRX: 148769902 -148798928
Locus: Xq28
Gene Diseases
The DIAPH2 MAGEA11 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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