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DHX8-SPACA3 Fusion FISH Probe

The DHX8-SPACA3 Fusion FISH Probe is used to confirm a fusion of the DHX8 and SPACA3 genes. The fusion of the DHX8 and SPACA3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DHX8-SPACA3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DHX8-SPACA3-20-RERE 20 (40 μL) 200 μL
DHX8-SPACA3-20-REOR 20 (40 μL) 200 μL
DHX8-SPACA3-20-REGO 20 (40 μL) 200 μL
DHX8-SPACA3-20-REGR 20 (40 μL) 200 μL
DHX8-SPACA3-20-REAQ 20 (40 μL) 200 μL
DHX8-SPACA3-20-ORRE 20 (40 μL) 200 μL
DHX8-SPACA3-20-OROR 20 (40 μL) 200 μL
DHX8-SPACA3-20-ORGO 20 (40 μL) 200 μL
DHX8-SPACA3-20-ORAQ 20 (40 μL) 200 μL
DHX8-SPACA3-20-GORE 20 (40 μL) 200 μL
DHX8-SPACA3-20-GOOR 20 (40 μL) 200 μL
DHX8-SPACA3-20-GOGO 20 (40 μL) 200 μL
DHX8-SPACA3-20-GOGR 20 (40 μL) 200 μL
DHX8-SPACA3-20-GOAQ 20 (40 μL) 200 μL
DHX8-SPACA3-20-GRRE 20 (40 μL) 200 μL
DHX8-SPACA3-20-GROR 20 (40 μL) 200 μL
DHX8-SPACA3-20-GRGO 20 (40 μL) 200 μL
DHX8-SPACA3-20-GRGR 20 (40 μL) 200 μL
DHX8-SPACA3-20-GRAQ 20 (40 μL) 200 μL
DHX8-SPACA3-20-AQRE 20 (40 μL) 200 μL
DHX8-SPACA3-20-AQOR 20 (40 μL) 200 μL
DHX8-SPACA3-20-AQGO 20 (40 μL) 200 μL
DHX8-SPACA3-20-AQGR 20 (40 μL) 200 μL
DHX8-SPACA3-20-AQAQ 20 (40 μL) 200 μL

DHX8 Gene Summary

This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Gene Name: DEAH-box Helicase 8

Chromosome: CHR17: 41561333 -41601680

Locus: 17q21.31

SPACA3 Gene Summary

The protein encoded by this gene is a sperm surface protein that may be involved in adhesion to the egg prior to fertilization. While the encoded protein has significant similarity to lysozyme at the amino acid level, it has no detectable bacteriocidal activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Gene Name: Sperm Acrosome Associated 3

Chromosome: CHR17: 31318881 -31324892

Locus: 17q11.2

Gene Diseases

The DHX8 SPACA3 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.