DHX8-MSI2 Fusion FISH Probe
The DHX8-MSI2 Fusion FISH Probe is used to confirm a fusion of the DHX8 and MSI2 genes. The fusion of the DHX8 and MSI2 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DHX8-MSI2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-RERE | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-REOR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-REGO | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-REGR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-REAQ | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-ORRE | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-OROR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-ORGO | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GORE | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GOOR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GOGO | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GOGR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GRRE | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GROR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GRGO | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GRGR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-AQRE | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-AQOR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-AQGO | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-AQGR | 20 (40 μL) | 200 μL |
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| DHX8-MSI2-20-AQAQ | 20 (40 μL) | 200 μL |
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DHX8 Gene Summary
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Gene Name: DEAH-box Helicase 8
Chromosome: CHR17: 41561333 -41601680
Locus: 17q21.31
MSI2 Gene Summary
This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
Gene Name: Musashi RNA Binding Protein 2
Chromosome: CHR17: 55333930 -55757299
Locus: 17q22
Gene Diseases
The DHX8 MSI2 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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