DHX57-SOS1 Fusion FISH Probe
The DHX57-SOS1 Fusion FISH Probe is used to confirm a fusion of the DHX57 and SOS1 genes. The fusion of the DHX57 and SOS1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DHX57-SOS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-RERE | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-REOR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-REGO | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-REGR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-REAQ | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-ORRE | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-OROR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-ORGO | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GORE | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GOOR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GOGO | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GOGR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GRRE | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GROR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GRGO | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GRGR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-AQRE | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-AQOR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-AQGO | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-AQGR | 20 (40 μL) | 200 μL |
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| DHX57-SOS1-20-AQAQ | 20 (40 μL) | 200 μL |
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SOS1 Gene Summary
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
Gene Name: SOS Ras/Rac Guanine Nucleotide Exchange Factor 1
Chromosome: CHR2: 39208689 -39347604
Locus: 2p22.1
DHX57 Gene Summary
The DExH-box Helicase 57 (DHX57) gene is located on chr2 :39024875-39103021 at 2p22.1.
Gene Name: DExH-box Helicase 57
Chromosome: CHR2: 39024875 -39103021
Locus: 2p22.1
Gene Diseases
The DHX57 SOS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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