DHX35-TOX2 Fusion FISH Probe
The DHX35-TOX2 Fusion FISH Probe is used to confirm a fusion of the DHX35 and TOX2 genes. The fusion of the DHX35 and TOX2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DHX35-TOX2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-RERE | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-REOR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-REGO | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-REGR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-REAQ | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-ORRE | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-OROR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-ORGO | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GORE | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GOOR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GOGO | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GOGR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GRRE | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GROR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GRGO | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GRGR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-AQRE | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-AQOR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-AQGO | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-AQGR | 20 (40 μL) | 200 μL |
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| DHX35-TOX2-20-AQAQ | 20 (40 μL) | 200 μL |
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DHX35 Gene Summary
DEAD box proteins characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The function of this gene product which is a member of this family, has not been determined. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Name: DEAH-box Helicase 35
Chromosome: CHR20: 37590980 -37668366
Locus: 20q11.23-q12
TOX2 Gene Summary
The TOX High Mobility Group Box Family Member 2 (TOX2) gene is located on chr20 :42543491-42698254 at 20q13.12.
Gene Name: TOX High Mobility Group Box Family Member 2
Chromosome: CHR20: 42543491 -42698254
Locus: 20q13.12
Gene Diseases
The DHX35 TOX2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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