DHRS1-METTL3 Fusion FISH Probe
The DHRS1-METTL3 Fusion FISH Probe is used to confirm a fusion of the DHRS1 and METTL3 genes. The fusion of the DHRS1 and METTL3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DHRS1-METTL3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-RERE | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-REOR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-REGO | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-REGR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-REAQ | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-ORRE | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-OROR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-ORGO | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-ORAQ | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GORE | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GOOR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GOGO | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GOGR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GOAQ | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GRRE | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GROR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GRGO | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GRGR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-GRAQ | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-AQRE | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-AQOR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-AQGO | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-AQGR | 20 (40 μL) | 200 μL |
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| DHRS1-METTL3-20-AQAQ | 20 (40 μL) | 200 μL |
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METTL3 Gene Summary
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]
Gene Name: Methyltransferase Like 3
Chromosome: CHR14: 21966281 -21979457
Locus: 14q11.2
DHRS1 Gene Summary
This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Gene Name: Dehydrogenase/reductase 1
Chromosome: CHR14: 24759803 -24769039
Locus: 14q12
Gene Diseases
The DHRS1 METTL3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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