DHCR24-THBS1 Fusion FISH Probe
The DHCR24-THBS1 Fusion FISH Probe is used to confirm a fusion of the DHCR24 and THBS1 genes. The fusion of the DHCR24 and THBS1 genes has been associated with Head And Neck Squamous Cell Carcinoma , and Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DHCR24-THBS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-RERE | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-REOR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-REGO | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-REGR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-REAQ | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-ORRE | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-OROR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-ORGO | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GORE | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GOOR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GOGO | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GOGR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GRRE | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GROR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GRGO | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GRGR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-AQRE | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-AQOR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-AQGO | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-AQGR | 20 (40 μL) | 200 μL |
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| DHCR24-THBS1-20-AQAQ | 20 (40 μL) | 200 μL |
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DHCR24 Gene Summary
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
Gene Name: 24-dehydrocholesterol Reductase
Chromosome: CHR1: 55315299 -55352921
Locus: 1p32.3
THBS1 Gene Summary
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]
Gene Name: Thrombospondin 1
Chromosome: CHR15: 39873279 -39889668
Locus: 15q14
Gene Diseases
The DHCR24 THBS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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