DHCR24-SIAE Fusion FISH Probe
The DHCR24-SIAE Fusion FISH Probe is used to confirm a fusion of the DHCR24 and SIAE genes. The fusion of the DHCR24 and SIAE genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DHCR24-SIAE-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-RERE | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-REOR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-REGO | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-REGR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-OROR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GORE | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GROR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| DHCR24-SIAE-20-AQAQ | 20 (40 μL) | 200 μL |
|
DHCR24 Gene Summary
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
Gene Name: 24-dehydrocholesterol Reductase
Chromosome: CHR1: 55315299 -55352921
Locus: 1p32.3
SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
Gene Diseases
The DHCR24 SIAE Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|