DHCR24-PRKCSH Fusion FISH Probe
The DHCR24-PRKCSH Fusion FISH Probe is used to confirm a fusion of the DHCR24 and PRKCSH genes. The fusion of the DHCR24 and PRKCSH genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DHCR24-PRKCSH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-RERE | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-REOR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-REGO | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-REGR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-REAQ | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-ORRE | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-OROR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-ORGO | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-ORAQ | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GORE | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GOOR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GOGO | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GOGR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GOAQ | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GRRE | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GROR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GRGO | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GRGR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-GRAQ | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-AQRE | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-AQOR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-AQGO | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-AQGR | 20 (40 μL) | 200 μL |
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| DHCR24-PRKCSH-20-AQAQ | 20 (40 μL) | 200 μL |
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DHCR24 Gene Summary
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
Gene Name: 24-dehydrocholesterol Reductase
Chromosome: CHR1: 55315299 -55352921
Locus: 1p32.3
PRKCSH Gene Summary
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Name: Protein Kinase C Substrate 80K-H
Chromosome: CHR19: 11546268 -11561782
Locus: 19p13.2
Gene Diseases
The DHCR24 PRKCSH Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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