DGUOK-STAMBP Fusion FISH Probe
The DGUOK-STAMBP Fusion FISH Probe is used to confirm a fusion of the DGUOK and STAMBP genes. The fusion of the DGUOK and STAMBP genes has been associated with Bladder Urothelial Carcinoma, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DGUOK-STAMBP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-RERE | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-REOR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-REGO | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-REGR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-REAQ | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-ORRE | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-OROR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-ORGO | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-ORAQ | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GORE | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GOOR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GOGO | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GOGR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GOAQ | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GRRE | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GROR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GRGO | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GRGR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-GRAQ | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-AQRE | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-AQOR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-AQGO | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-AQGR | 20 (40 μL) | 200 μL |
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| DGUOK-STAMBP-20-AQAQ | 20 (40 μL) | 200 μL |
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DGUOK Gene Summary
In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Deoxyguanosine Kinase
Chromosome: CHR2: 74153952 -74186088
Locus: 2p13.1
STAMBP Gene Summary
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: STAM Binding Protein
Chromosome: CHR2: 74056042 -74094295
Locus: 2p13.1
Gene Diseases
The DGUOK STAMBP Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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