DGCR8-ITGA2 Fusion FISH Probe
The DGCR8-ITGA2 Fusion FISH Probe is used to confirm a fusion of the DGCR8 and ITGA2 genes. The fusion of the DGCR8 and ITGA2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DGCR8-ITGA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-RERE | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-REOR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-REGO | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-REGR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-REAQ | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-ORRE | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-OROR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-ORGO | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GORE | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GOOR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GOGO | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GOGR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GRRE | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GROR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GRGO | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GRGR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-AQRE | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-AQOR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-AQGO | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-AQGR | 20 (40 μL) | 200 μL |
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| DGCR8-ITGA2-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGA2 Gene Summary
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Name: Integrin Subunit Alpha 2
Chromosome: CHR5: 52285155 -52390609
Locus: 5q11.2
DGCR8 Gene Summary
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Gene Name: DGCR8, Microprocessor Complex Subunit
Chromosome: CHR22: 20067754 -20099400
Locus: 22q11.21
Gene Diseases
The DGCR8 ITGA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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