DGCR2-IRX4 Fusion FISH Probe
The DGCR2-IRX4 Fusion FISH Probe is used to confirm a fusion of the DGCR2 and IRX4 genes. The fusion of the DGCR2 and IRX4 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DGCR2-IRX4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-RERE | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-REOR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-REGO | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-REGR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-REAQ | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-ORRE | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-OROR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-ORGO | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-ORAQ | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GORE | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GOOR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GOGO | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GOGR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GOAQ | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GRRE | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GROR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GRGO | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GRGR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-GRAQ | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-AQRE | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-AQOR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-AQGO | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-AQGR | 20 (40 μL) | 200 μL |
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| DGCR2-IRX4-20-AQAQ | 20 (40 μL) | 200 μL |
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DGCR2 Gene Summary
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: DiGeorge Syndrome Critical Region Gene 2
Chromosome: CHR22: 19023794 -19109967
Locus: 22q11.21
IRX4 Gene Summary
The Iroquois Homeobox 4 (IRX4) gene is located on chr5 :1877540-1882880 at 5p15.33.
Gene Name: Iroquois Homeobox 4
Chromosome: CHR5: 1877540 -1882880
Locus: 5p15.33
Gene Diseases
The DGCR2 IRX4 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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