DERL1-C6ORF132 Fusion FISH Probe
The DERL1-C6ORF132 Fusion FISH Probe is used to confirm a fusion of the DERL1 and C6ORF132 genes. The fusion of the DERL1 and C6ORF132 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DERL1-C6ORF132-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-RERE | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-REOR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-REGO | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-REGR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-REAQ | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-ORRE | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-OROR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-ORGO | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-ORAQ | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GORE | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GOOR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GOGO | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GOGR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GOAQ | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GRRE | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GROR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GRGO | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GRGR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-GRAQ | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-AQRE | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-AQOR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-AQGO | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-AQGR | 20 (40 μL) | 200 μL |
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| DERL1-C6ORF132-20-AQAQ | 20 (40 μL) | 200 μL |
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DERL1 Gene Summary
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Name: Derlin 1
Chromosome: CHR8: 124025567 -124054648
Locus: 8q24.13
C6orf132 Gene Summary
The Chromosome 6 Open Reading Frame 132 (C6orf132) gene is located on chr6 :42068856-42110715 at 6p21.1.
Gene Name: Chromosome 6 Open Reading Frame 132
Chromosome: CHR6: 42068856 -42110715
Locus: 6p21.1
Gene Diseases
The DERL1 C6ORF132 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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