DENR-KNTC1 Fusion FISH Probe
The DENR-KNTC1 Fusion FISH Probe is used to confirm a fusion of the DENR and KNTC1 genes. The fusion of the DENR and KNTC1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DENR-KNTC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-RERE | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-REOR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-REGO | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-REGR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-REAQ | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-ORRE | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-OROR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-ORGO | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GORE | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GOOR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GOGO | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GOGR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GRRE | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GROR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GRGO | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GRGR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-AQRE | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-AQOR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-AQGO | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-AQGR | 20 (40 μL) | 200 μL |
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| DENR-KNTC1-20-AQAQ | 20 (40 μL) | 200 μL |
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DENR Gene Summary
This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008]
Gene Name: Density Regulated Re-initiation And Release Factor
Chromosome: CHR12: 123237370 -123255953
Locus: 12q24.31
KNTC1 Gene Summary
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. [provided by RefSeq, Jul 2008]
Gene Name: Kinetochore Associated 1
Chromosome: CHR12: 123011808 -123110947
Locus: 12q24.31
Gene Diseases
The DENR KNTC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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