DENND5B-NUP54 Fusion FISH Probe
The DENND5B-NUP54 Fusion FISH Probe is used to confirm a fusion of the DENND5B and NUP54 genes. The fusion of the DENND5B and NUP54 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DENND5B-NUP54-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-RERE | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-REOR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-REGO | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-REGR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-REAQ | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-ORRE | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-OROR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-ORGO | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-ORAQ | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GORE | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GOOR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GOGO | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GOGR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GOAQ | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GRRE | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GROR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GRGO | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GRGR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-GRAQ | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-AQRE | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-AQOR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-AQGO | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-AQGR | 20 (40 μL) | 200 μL |
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| DENND5B-NUP54-20-AQAQ | 20 (40 μL) | 200 μL |
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NUP54 Gene Summary
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
Gene Name: Nucleoporin 54
Chromosome: CHR4: 77035816 -77069655
Locus: 4q21.1
DENND5B Gene Summary
The DENN Domain Containing 5B (DENND5B) gene is located on chr12 :31535156-31743952 at 12p11.21.
Gene Name: DENN Domain Containing 5B
Chromosome: CHR12: 31535156 -31743952
Locus: 12p11.21
Gene Diseases
The DENND5B NUP54 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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