DENND2C-AMPD1 Fusion FISH Probe
The DENND2C-AMPD1 Fusion FISH Probe is used to confirm a fusion of the DENND2C and AMPD1 genes. The fusion of the DENND2C and AMPD1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DENND2C-AMPD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-RERE | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-REOR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-REGO | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-REGR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-REAQ | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-ORRE | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-OROR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-ORGO | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GORE | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GOOR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GOGO | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GOGR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GRRE | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GROR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GRGO | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GRGR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-AQRE | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-AQOR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-AQGO | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-AQGR | 20 (40 μL) | 200 μL |
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| DENND2C-AMPD1-20-AQAQ | 20 (40 μL) | 200 μL |
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AMPD1 Gene Summary
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Gene Name: Adenosine Monophosphate Deaminase 1
Chromosome: CHR1: 115215719 -115238239
Locus: 1p13.2
DENND2C Gene Summary
The DENN Domain Containing 2C (DENND2C) gene is located on chr1 :115127195-115212732 at 1p13.2.
Gene Name: DENN Domain Containing 2C
Chromosome: CHR1: 115127195 -115212732
Locus: 1p13.2
Gene Diseases
The DENND2C AMPD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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