DDX23-RND1 Fusion FISH Probe
The DDX23-RND1 Fusion FISH Probe is used to confirm a fusion of the DDX23 and RND1 genes. The fusion of the DDX23 and RND1 genes has been associated with Liver Hepatocellular Carcinoma, and Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDX23-RND1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-RERE | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-REOR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-REGO | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-REGR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-REAQ | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-ORRE | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-OROR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-ORGO | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GORE | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GOOR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GOGO | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GOGR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GRRE | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GROR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GRGO | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GRGR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-AQRE | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-AQOR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-AQGO | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-AQGR | 20 (40 μL) | 200 μL |
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| DDX23-RND1-20-AQAQ | 20 (40 μL) | 200 μL |
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DDX23 Gene Summary
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: DEAD-box Helicase 23
Chromosome: CHR12: 49223538 -49245957
Locus: 12q13.12
RND1 Gene Summary
This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014]
Gene Name: Rho Family GTPase 1
Chromosome: CHR12: 49250915 -49259653
Locus: 12q13.12
Gene Diseases
The DDX23 RND1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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