DDX23-NMNAT2 Fusion FISH Probe
The DDX23-NMNAT2 Fusion FISH Probe is used to confirm a fusion of the DDX23 and NMNAT2 genes. The fusion of the DDX23 and NMNAT2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDX23-NMNAT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-RERE | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-REOR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-REGO | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-REGR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-REAQ | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-ORRE | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-OROR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-ORGO | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GORE | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GOOR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GOGO | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GOGR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GRRE | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GROR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GRGO | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GRGR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-AQRE | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-AQOR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-AQGO | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-AQGR | 20 (40 μL) | 200 μL |
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| DDX23-NMNAT2-20-AQAQ | 20 (40 μL) | 200 μL |
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DDX23 Gene Summary
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: DEAD-box Helicase 23
Chromosome: CHR12: 49223538 -49245957
Locus: 12q13.12
NMNAT2 Gene Summary
This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Nicotinamide Nucleotide Adenylyltransferase 2
Chromosome: CHR1: 183217371 -183387634
Locus: 1q25.3
Gene Diseases
The DDX23 NMNAT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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