DDX20-TBX15 Fusion FISH Probe
The DDX20-TBX15 Fusion FISH Probe is used to confirm a fusion of the DDX20 and TBX15 genes. The fusion of the DDX20 and TBX15 genes has been associated with Acute Myeloid Leukemia. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDX20-TBX15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-RERE | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-REOR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-REGO | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-REGR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-REAQ | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-ORRE | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-OROR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-ORGO | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GORE | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GOOR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GOGO | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GOGR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GRRE | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GROR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GRGO | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GRGR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-AQRE | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-AQOR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-AQGO | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-AQGR | 20 (40 μL) | 200 μL |
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| DDX20-TBX15-20-AQAQ | 20 (40 μL) | 200 μL |
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TBX15 Gene Summary
This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009]
Gene Name: T-box 15
Chromosome: CHR1: 119425665 -119532179
Locus: 1p12
DDX20 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008]
Gene Name: DEAD-box Helicase 20
Chromosome: CHR1: 112298189 -112310199
Locus: 1p13.2
Gene Diseases
The DDX20 TBX15 Fusion has been associated with the following diseases:
| Disease Name |
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| Acute Myeloid Leukemia |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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