DDX17-CPT1B Fusion FISH Probe
The DDX17-CPT1B Fusion FISH Probe is used to confirm a fusion of the DDX17 and CPT1B genes. The fusion of the DDX17 and CPT1B genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDX17-CPT1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-RERE | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-REOR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-REGO | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-REGR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-REAQ | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-ORRE | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-OROR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-ORGO | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GORE | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GOOR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GOGO | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GOGR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GRRE | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GROR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GRGO | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GRGR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-AQRE | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-AQOR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-AQGO | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-AQGR | 20 (40 μL) | 200 μL |
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| DDX17-CPT1B-20-AQAQ | 20 (40 μL) | 200 μL |
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CPT1B Gene Summary
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]
Gene Name: Carnitine Palmitoyltransferase 1B
Chromosome: CHR22: 51007289 -51017096
Locus: 22q13.33
DDX17 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011]
Gene Name: DEAD-box Helicase 17
Chromosome: CHR22: 38879442 -38902345
Locus: 22q13.1
Gene Diseases
The DDX17 CPT1B Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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