DDI2-C4BPB Fusion FISH Probe
The DDI2-C4BPB Fusion FISH Probe is used to confirm a fusion of the DDI2 and C4BPB genes. The fusion of the DDI2 and C4BPB genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DDI2-C4BPB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-RERE | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-REOR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-REGO | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-REGR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-REAQ | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-ORRE | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-OROR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-ORGO | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-ORAQ | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GORE | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GOOR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GOGO | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GOGR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GOAQ | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GRRE | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GROR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GRGO | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GRGR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-GRAQ | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-AQRE | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-AQOR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-AQGO | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-AQGR | 20 (40 μL) | 200 μL |
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| DDI2-C4BPB-20-AQAQ | 20 (40 μL) | 200 μL |
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C4BPB Gene Summary
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: Complement Component 4 Binding Protein Beta
Chromosome: CHR1: 207262211 -207273337
Locus: 1q32.1
DDI2 Gene Summary
The DNA Damage Inducible 1 Homolog 2 (DDI2) gene is located on chr1 :15943952-15987552 at 1p36.21.
Gene Name: DNA Damage Inducible 1 Homolog 2
Chromosome: CHR1: 15943952 -15987552
Locus: 1p36.21
Gene Diseases
The DDI2 C4BPB Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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