DCAKD-PLCD3 Fusion FISH Probe
The DCAKD-PLCD3 Fusion FISH Probe is used to confirm a fusion of the DCAKD and PLCD3 genes. The fusion of the DCAKD and PLCD3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DCAKD-PLCD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-RERE | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-REOR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-REGO | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-REGR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-REAQ | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-ORRE | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-OROR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-ORGO | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GORE | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GOOR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GOGO | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GOGR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GRRE | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GROR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GRGO | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GRGR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-AQRE | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-AQOR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-AQGO | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-AQGR | 20 (40 μL) | 200 μL |
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| DCAKD-PLCD3-20-AQAQ | 20 (40 μL) | 200 μL |
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DCAKD Gene Summary
The Dephospho-CoA Kinase Domain Containing (DCAKD) gene is located on chr17 :43100705-43138473 at 17q21.31.
Gene Name: Dephospho-CoA Kinase Domain Containing
Chromosome: CHR17: 43100705 -43138473
Locus: 17q21.31
PLCD3 Gene Summary
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008]
Gene Name: Phospholipase C Delta 3
Chromosome: CHR17: 43189007 -43209891
Locus: 17q21.31
Gene Diseases
The DCAKD PLCD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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