DCAF6-YEATS4 Fusion FISH Probe
The DCAF6-YEATS4 Fusion FISH Probe is used to confirm a fusion of the DCAF6 and YEATS4 genes. The fusion of the DCAF6 and YEATS4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DCAF6-YEATS4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-RERE | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-REOR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-REGO | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-REGR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-REAQ | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-ORRE | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-OROR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-ORGO | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-ORAQ | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GORE | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GOOR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GOGO | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GOGR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GOAQ | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GRRE | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GROR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GRGO | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GRGR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-GRAQ | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-AQRE | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-AQOR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-AQGO | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-AQGR | 20 (40 μL) | 200 μL |
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| DCAF6-YEATS4-20-AQAQ | 20 (40 μL) | 200 μL |
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YEATS4 Gene Summary
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Name: YEATS Domain Containing 4
Chromosome: CHR12: 69753531 -69784576
Locus: 12q15
DCAF6 Gene Summary
The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]
Gene Name: DDB1 And CUL4 Associated Factor 6
Chromosome: CHR1: 167905796 -168045083
Locus: 1q24.2
Gene Diseases
The DCAF6 YEATS4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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