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DBF4B-DYNC2H1 Fusion FISH Probe

The DBF4B-DYNC2H1 Fusion FISH Probe is used to confirm a fusion of the DBF4B and DYNC2H1 genes. The fusion of the DBF4B and DYNC2H1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DBF4B-DYNC2H1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-RERE 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-REOR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-REGO 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-REGR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-REAQ 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-ORRE 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-OROR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-ORGO 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-ORAQ 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GORE 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GOOR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GOGO 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GOGR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GOAQ 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GRRE 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GROR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GRGO 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GRGR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-GRAQ 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-AQRE 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-AQOR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-AQGO 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-AQGR 20 (40 μL) 200 μL
DBF4B-DYNC2H1-20-AQAQ 20 (40 μL) 200 μL

DYNC2H1 Gene Summary

This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]

Gene Name: Dynein Cytoplasmic 2 Heavy Chain 1

Chromosome: CHR11: 102980159 -103350591

Locus: 11q22.3

DBF4B Gene Summary

This gene encodes a regulator of the cell division cycle 7 homolog (S. cerevisiae) protein, a serine-threonine kinase which links cell cycle regulation to genome duplication. This protein localizes to the nucleus and, in complex with the cell division cycle 7 homolog (S. cerevisiae) protein, may facilitate M phase progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

Gene Name: DBF4 Zinc Finger B

Chromosome: CHR17: 42785975 -42829636

Locus: 17q21

Gene Diseases

The DBF4B DYNC2H1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.