DAG1-LARS2 Fusion FISH Probe
The DAG1-LARS2 Fusion FISH Probe is used to confirm a fusion of the DAG1 and LARS2 genes. The fusion of the DAG1 and LARS2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DAG1-LARS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-RERE | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-REOR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-REGO | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-REGR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-REAQ | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-ORRE | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-OROR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-ORGO | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GORE | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GOOR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GOGO | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GOGR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GRRE | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GROR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GRGO | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GRGR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-AQRE | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-AQOR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-AQGO | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-AQGR | 20 (40 μL) | 200 μL |
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| DAG1-LARS2-20-AQAQ | 20 (40 μL) | 200 μL |
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DAG1 Gene Summary
This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Nov 2015]
Gene Name: Dystroglycan 1
Chromosome: CHR3: 49506145 -49573048
Locus: 3p21.31
LARS2 Gene Summary
This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]
Gene Name: Leucyl-tRNA Synthetase 2, Mitochondrial
Chromosome: CHR3: 45430074 -45590328
Locus: 3p21.31
Gene Diseases
The DAG1 LARS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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