DAB1-DRAM1 Fusion FISH Probe
The DAB1-DRAM1 Fusion FISH Probe is used to confirm a fusion of the DAB1 and DRAM1 genes. The fusion of the DAB1 and DRAM1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DAB1-DRAM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-RERE | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-REOR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-REGO | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-REGR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-REAQ | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-ORRE | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-OROR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-ORGO | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GORE | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GOOR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GOGO | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GOGR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GRRE | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GROR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GRGO | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GRGR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-AQRE | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-AQOR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-AQGO | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-AQGR | 20 (40 μL) | 200 μL |
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| DAB1-DRAM1-20-AQAQ | 20 (40 μL) | 200 μL |
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DAB1 Gene Summary
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
Gene Name: DAB1, Reelin Adaptor Protein
Chromosome: CHR1: 57463578 -58716211
Locus: 1p32.2
DRAM1 Gene Summary
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]
Gene Name: DNA Damage Regulated Autophagy Modulator 1
Chromosome: CHR12: 102271104 -102317401
Locus: 12q23.2
Gene Diseases
The DAB1 DRAM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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