DAAM1-HS6ST3 Fusion FISH Probe
The DAAM1-HS6ST3 Fusion FISH Probe is used to confirm a fusion of the DAAM1 and HS6ST3 genes. The fusion of the DAAM1 and HS6ST3 genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DAAM1-HS6ST3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-RERE | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-REOR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-REGO | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-REGR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-REAQ | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-ORRE | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-OROR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-ORGO | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-ORAQ | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GORE | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GOOR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GOGO | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GOGR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GOAQ | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GRRE | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GROR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GRGO | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GRGR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-GRAQ | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-AQRE | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-AQOR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-AQGO | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-AQGR | 20 (40 μL) | 200 μL |
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| DAAM1-HS6ST3-20-AQAQ | 20 (40 μL) | 200 μL |
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DAAM1 Gene Summary
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012]
Gene Name: Dishevelled Associated Activator Of Morphogenesis 1
Chromosome: CHR14: 59655398 -59836471
Locus: 14q23.1
HS6ST3 Gene Summary
Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000 [PubMed 10644753]).[supplied by OMIM, Mar 2008]
Gene Name: Heparan Sulfate 6-O-sulfotransferase 3
Chromosome: CHR13: 96743092 -97491812
Locus: 13q32.1
Gene Diseases
The DAAM1 HS6ST3 Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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